In 2023, advertising expenditure on weight-loss drugs by pharmaceutical giants Novo Nordisk and Eli Lilly experienced a remarkable 250% year-over-year increase in the United States, with Eli Lilly leading the surge. However, both companies have since reduced their ad spending due to intensifying supply chain issues leading to drug shortages and rising costs. Notably, Eli Lilly's new direct-to-consumer website, launched in February 2024 for ordering drugs like Zepbound, surpassed major pharmacy websites in average time spent.
Between mid-December 2023 and mid-March 2024, individuals targeted by Eli Lilly's ads saw a 350% increase in pharma ad impressions, with GlaxoSmithKline leading the increase. Eli Lilly is notably more active in targeting the Hispanic community, with about 33% of Mounjaro ads in Spanish, making up 12% of ad impressions, double Novo's share for Ozempic and Wegovy. This Spanish-language strategy focuses on diabetes management rather than weight loss.
Novo's ad impressions from weight-loss-themed ads peaked at over 500 million in Q4 2023, coinciding with Zepbound's launch. Variations in Novo's ad budget may explain over 60% of stock price movements, though the effect is non-linear, and other factors like product efficacy findings also influence stock performance.
TikTok for Business is promoting tiered first-30-day ad credit incentives for new self-serve SMB advertisers: spend $100 get $100, $500 get $500, or $1,500 get $1,500 plus 1-to-1 expert onboarding support, with a headline entry offer of 50% off first-month spend up to $200 and matching credits up to $6,000. Credits are applied within 7 days of hitting the highest threshold or after the 30-day accumulation window. Eligibility excludes agency, Business Center, and TikTok Shop accounts, and limits one ad account per new TikTok For Business account. For ad ops teams, these terms dictate budget pacing, account structure, and credit-expiry planning.
This TikTok for Business landing page promotes a limited-period new-advertiser incentive program offering up to USD 6,000 in matched ad credits. Three self-serve tiers are presented: 50% off first 30-day spend (up to $200), dollar-for-dollar match up to $500, and match up to $6,000. A separate headline offer advertises Spend $100/Get $100, Spend $500/Get $500, and Spend $1,500/Get $1,500 plus 1-to-1 expert onboarding support. Registration requires email or phone sign-up with 2-step verification. Eligibility is restricted to new SMB self-serve accounts, excluding agency, Business Center, and TikTok Shop accounts; credits post within 7 days of hitting the highest threshold or after the 30-day window.
TikTok video ads use short, engaging clips to promote brands. Effective ads start with a strong hook, include clear CTAs, use sound and text overlays, and test formats. TikTok offers In-Feed, TopView, Spark Ads, and more for diverse marketing.
Mobile in-game advertising balances revenue and player experience using formats like banners, interstitials, playables, videos, rewarded, and native ads. Each format varies in cost, engagement, and ROI across platforms, with no single best option—success depends on goals, budget, and platform-specific performance.
AppsFlyer’s 2026 creative data shows video and static image ads reward opposite creative qualities, so ad ops teams should plan, budget, and test them separately. Video spend is concentrating: gaming’s top 2% of video creatives captured 60.7% of spend, up from 53.5%, while image spend spread out. Top spenders are testing far more variations, widening the testing gap. Action/Strategy and Puzzle/Lifestyle show format-specific tone and social-proof reversals; Finance is the exception. Teams should use AI-assisted variation, analyze video winners deeply, keep broad image testing, and measure performance at attribute level.
TikTok's UK/Europe scale (30M+ UK, 200M+ EU) and content graph make category objections obsolete. For ad ops, success comes from relevance, not trends: proof-led demos, explainers, reviews, and problem-solving content can reach high-intent audiences without a large follower base. Case studies show material performance: Toyota CPA -38%, BCP 10x registrations, Randstad 2.81% CTR/17M impressions, Prep Kitchen +44% conversion and +374% orders with Smart+, PureGym CPA -77%, HydroClean cost per conversation -74%. Action: test utility/creator content, use Smart+ for scaled creative testing, layer TopView on trusted content, and target niche communities rather than broad reach.
The open internet offers vast, incremental scale for app marketers beyond walled gardens, but its complexity requires supply path optimization (SPO). With non-exclusive inventory and multiple bid requests per impression, advanced machine learning is crucial to select optimal paths, price bids accurately, and serve effective creatives in milliseconds.
Data connections link brand marketing data with TikTok Ads Manager, enabling improved measurement, advanced solutions like Catalog Ads, and custom audiences. Sharing onsite and offsite events through TikTok Events API or Pixel allows better ad delivery and performance. For e-commerce success, set up signals with required events and parameters, sync your product catalog, and confirm event-catalog match rate.
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